A drug fueled camping trip goes to hell when a militant killing machine stalks four teens through the wilderness, luring them toward an abandoned Army hospital. Weeks away from graduating high school. two young couples are in for the camping trip of their lives. Stocked up on drugs and alcohol, they journey to the desolate wilderness of Fossil Creek. Passing the last rural town, populated by fringe rednecks, they leave all the care in the world behind them. Stacy and Brandon are pulled away from a weekend of romance, the euphoria of their party quickly turning to fear when their classmates are kidnapped and tortured. Haley and Mike become captives of The Patient, a perverse, medically enhanced soldier. Over the night, they learn the horrid details of a science experiment gone wrong, one stemming from the government's post World War II research. The brainwashed assassin fulfills his program as the teens fight for their lives. With the help of Mike's slacker brother John, the torture chamber is located. Using his knowledge of the base from his own past military experience, John must make a last-ditch effort to save his friends - or die trying.
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